This holiday season drive safe and defensively. According the the US government there were 38,588 fatal collision in the US last year. Friday, Saturday and Sunday were the days most likely to be fatal with Saturday leading the pack. There was 1.29 deaths for every 100 million vehicle miles driven.
The federal government breaks the statistics down by state, month, day, and time. If you have interest go to www-fars.nhtsa.dot.gov/Crashes/CrashesTime.aspx and you can see and sort the numbers.